Ιούλ 29, 2022 | Medical News, Scientific articles, Επιστημονικά Άρθρα, Κλ. Μελέτες - Έρευνες
In previous studies, the cardio-ankle vascular index (CAVI) was increased significantly in idiopathic pulmonary arterial hypertension (IPAH) patients compared with the healthy group and did not differ much from that in systemic hypertensives. In this study, the...
Ιούλ 29, 2022 | Medical News, Scientific articles, Επιστημονικά Άρθρα, Κλ. Μελέτες - Έρευνες
Background: Pulmonary hypertension (PH) is characterized by increased right atrial (RA) stretch and pressure. The major genetic predisposing risk factor for PH involves mutations in bone morphogenetic protein (BMP) receptor 2 (BMPR2), for which BMP9 and BMP10 are...
Ιούλ 29, 2022 | Medical News, Scientific articles, Επιστημονικά Άρθρα, Κλ. Μελέτες - Έρευνες
Background: Oxygenated hemoglobin (OxyHem) in arterial blood may reflect disease severity in patients with systemic sclerosis (SSc), particularly among those with pulmonary manifestations, such as pulmonary hypertension (PH). Objectives: Hence, the aim of this study...
Ιούλ 27, 2022 | Medical News, Scientific articles, Επιστημονικά Άρθρα, Κλ. Μελέτες - Έρευνες
Background: Pulmonary arterial hypertension (PAH) is a serious condition that causes right heart failure. A persistent inflammatory process is present in the vascular endothelial tissue, which releases circulating CD34+,133+ endothelial progenitor cells (EPCs),...
Ιούλ 27, 2022 | Medical News, Scientific articles, Επιστημονικά Άρθρα, Κλ. Μελέτες - Έρευνες
Purpose: The REPLACE study showed that PAH patients treated with phosphodiesterase-5 inhibitors (PDE5i) still at intermediate risk could achieve clinical improvement when switched to riociguat. Significant improvements in risk status with riociguat versus PDE5i were...
Ιούλ 27, 2022 | Medical News, Scientific articles, Επιστημονικά Άρθρα, Κλ. Μελέτες - Έρευνες
Background: Digoxin increases cardiac output modestly in acute settings in patients with pulmonary arterial hypertension (PAH) and right ventricular failure; however, very little is known about the effects of chronic digoxin therapy in PAH. Methods: We studied 251...